Latest News

α1-Antitrypsin deficiency and the risk of COVID-19: an urgent call to action

The COVID-19 pandemic is a global emergency. Identifying populations who are at risk of severe complications is crucial in developing special measures to prevent or reduce severe illness and mortality in vulnerable patients. Emerging evidence indicat
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Z Factor to host a virtual meeting for Alpha-1 Awareness to give a summary of their trial medicine and their overall programme

  We were pleased to announce back in August 2020 that the first person was dosed with ZF874, a potential treatment for alpha-1-antitrypsin deficiency.  Then on the 24th September we published the details for HMR who are running the trail on beh
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HMR Opens up their trial for people with one or two faulty ‘Z’ alleles.

At the beginning of their trial, HMR were looking for healthy PiMZ people to partake in their new clinical trial.  We are pleased to say that they have now opened it up to people with one or two ‘Z’ alleles.  If you are PiMZ, PiSZ, or PiZ
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New blood test predicts which COVID-19 patients will develop severe infection

18th October 2020      Prof. Gerry McElvaney, Chairman of the Department of Medicine and Vice Dean of the School of Medicine, Royal College of Surgeons in Ireland and Prof. Gerard Curley,   Professor of Anaesthesia and Critical Care at
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Vertex Abandons VX-814 Program for Treating Rare Liver Disease

18th October 2020   Vertex Pharmaceuticals announced that based on early data of its Phase II trial of VX-814 in Alpha-1 antitrypsin deficiency (AATD), it is halting the trial and ending development of the drug. AATD is a genetic disease resulti
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BBC documentary Surgeons: At the edge of life will show AATD patient receive a double lung transplant.

On Tuesday 20 October, the BBC documentary Surgeons: At the edge of life will show David (pictured below) receiving a double lung transplant. David received his new lungs earlier this year at the Royal Papworth Hospital, Cambridge. The show airs on B
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