Welcome to Alpha-1 Awareness, a UK Charity that Supports people with AATD – (BACKUP)

AATD or Alpha-1 Antitrypsin Deficiency is a lack of the protein alpha-1 antitrypsin (AAT) which is produced in the liver. The main job of AAT is to protect the lungs. A deficiency can lead to life-threatening lung and/or liver disease.

The first signs and symptoms of lung disease caused by alpha-1 antitrypsin deficiency usually appear between ages 20 and 50.
The symptoms are:

  • shortness of breath following mild activity
  • reduced ability to exercise
  • wheezing

About ten percent of infants with the deficiency show signs of liver damage at birth. Fifteen percent of adult Alphas also develop liver disease.

Only a small fraction of alpha-1 antitrypsin deficient patients in the United Kingdom are aware of the causes of their condition.

Our charity is run by non-paid volunteers who all are either affected by Alpha-1 or have a family member who is. We all have a connection to Alpha-1 and this isn’t our day job. We have a real passion for the charity and for supporting people who are affected, their families and friends.

This website was created so that people can learn more about Alpha-1 and how to get support.  We produce our own booklets which people can download and view digitally (click here) and even request that a set be sent to them in the post for free. We have a private Facebook Group where we help to support people in a safe environment. If you would prefer one on one support, then you can email us directly on ‘support@alpha1.uk‘ or use our Contacts Us Form. We care, we want to help those affected, their families and their friends. We are also proud to be the only UK charity that is donating money to go directly to the research of a cure.

 


 

Fund raisers

We would like to thank all those that raise funds for us, without you, we would not have a charity & we would not be able to support those affected with Alpha-1 and their families.
Please help the below people by reading their stories, if you are able, please make a donation.

British 10K Run

Date: Sunday 21st July 2019
Location: London

We would like to thank all those that raise funds for us, without you, we would not have a charity & we would not be able to support those affected with Alpha-1 and their families.
Please help the below people by reading their stories, if you are able, please make a donation.

TrekFest ~ The Peaks

Date: Saturday 31st August 2019
Location: Hope Valley, Derbyshire (S33 8RZ)

We would like to thank all those that raise funds for us, without you, we would not have a charity & we would not be able to support those affected with Alpha-1 and their families.
Please help the below people by reading their stories, if you are able, please make a donation.


 Latest News

 

RCSI team to start trial for promising Covid-19 therapy for severe infections

Researchers in Ireland are hoping to add to the growing list of drug candidates for the treatment of patients with severe Covid-19 infection. A team from the Royal College of Surgeons in Ireland (RCSI) has published a paper in the American Journal of
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New Board members to our charity

Alpha-1 Awareness is a charity founded and run by volunteers to help bring awareness of AATD as well as give support to those affected, their families, friends and carers.  We can’t do this alone, and we are so thankful to those who help in our Faceb
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AlphaNet Announces New Appointment to the Board of Directors

AlphaNet is pleased to announce the appointment of Dell Witcher to the board of directors, effective May 14, 2020. “Dell’s expertise and involvement in our board will greatly benefit the Alpha-1 community.” “We are excited to welcome Dell to AlphaNet
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Arrowhead Pharmaceuticals: Pushing the Boundaries of Gene Silencing

RNA interference (RNAi), sometimes called gene silencing, is an approach to therapeutics in certain diseases that are caused by the production of abnormal proteins or an overproduction of proteins, which can be treated by turning off or silencing the
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‘Grey’s Anatomy’ TV Show’s episode about Alpha-1

[Warning: The below contains MAJOR spoilers for Season 16, Episode 15 of Grey’s Anatomy, “Snowblind.”] The blizzard isn’t the only disaster in this Grey’s Anatomy episode—Season 16, Episode 15 Hayes’ patient this week is Elisa, a 6-year-old with alph
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Alpha-1 Awareness donate £10,000 to the research of a cure

On Monday 3rd February 2020, Alan and Emma Wooler of Alpha-1 Awareness went to UCL (University College London) to see Professor David Lomas, and presented him with a cheque for £10,000 to go towards his research of a cure for Alpha-1.   Alan Woo
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Researchers build a better lung model

30th January 2020   (Boston)–Using a combination of pluripotent stem cells (cells that can potentially produce any cell or tissue type) and machine learning (artificial intelligence that allows computers to learn automatically), researcher
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Danish Medicines Council Grants Approval for CSL Behring’s Respreeza as Standard Treatment for Severe Alpha-1 Antitrypsin Deficiency Patients

HATTERSHEIM AM MAIN, Germany, Jan. 24, 2020 /PRNewswire/ — Global biotherapeutics leader CSL Behring today announced that the Danish Medicines Council has published its final decision, approving human Alpha 1 Antitrypsin  (AAT) therapy and Resp
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This website is run by Alphas and their carers. We do our very best to ensure that all information shown here is up-to-date and accurate. However, you should always consult your own GP or other medical professional if you have the slightest concerns about your health.